An animal’s biologic response in trying to deal with a threat to its internal equilibrium (homeostasis) by internal and external stressors. A failure to do so may lead to ‘distressDistress It indicates a disadvantageous environment in which the animal is no longer able to adapt in a biologically successful manner to the stressors to which it is exposed. One speaks of distress when the level or the duration of stress are such that significant changes in biological function are required to survive.’ resulting in an inability to cope, leading to poor welfareWelfare A complex and dynamic internal state that includes: successful biologic functioning, positive experiences, and absence of negative conditions. The animal adapts effectively to internal needs and external stimuli and maintains a good mental state..