Dried reddish-brown secretionsSecretion The production of fluids by glandular organs or tissues in the body. of the Harderian gland (porphyrins). An increased production or decreased removal of porphyrin is indicative of reduced well-beingWell-being A complex and dynamic internal state that includes: successful biologic functioning, positive experiences, and absence of negative conditions. The animal adapts effectively to internal needs and external stimuli and maintains a good mental state. and can frequently be observed in stressed rats. It may also be a sign of less meticulous groomingGrooming The behavior animals engage in to keep clean. Grooming removes dirt from fur and body openings. Absence of this behavior indicates reduced well-being..